Ownership Submission
FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Lipschultz Tyler
 2. Date of Event Requiring Statement (Month/Day/Year)
01/03/2011		 3. Issuer Name and Ticker or Trading Symbol
NUVASIVE INC [NUVA]
(Last)
(First)
(Middle)
7475 LUSK BLVD.		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
EVP, Biologics
 5. If Amendment, Date Original Filed(Month/Day/Year)
01/05/2011
(Street)

SAN DIEGO, CA 92121		 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 2,451 (1)
D
 
Common Stock 6,300 (2)
D
 
Common Stock 9,000 (3)
D
 

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (Right to Buy)   (4) 06/30/2018 Common Stock 75,000 $ 44.66 D  
Stock Option (Right to Buy)   (5) 01/02/2019 Common Stock 25,000 $ 34.82 D  
Stock Option (Right to Buy)   (6) 02/19/2020 Common Stock 22,500 $ 29.95 D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Lipschultz Tyler
7475 LUSK BLVD.
SAN DIEGO, CA 92121		       EVP, Biologics  

Signatures

Jason Hannon, Attorney-In-Fact 02/04/2011
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Includes 525 shares acquired by the Reporting Person under the Issuer's Employee Stock Purchase Plan on April 30, 2009 and 713 shares acquired by the Reporting Person under the Issuer's Employee Stock Purchase Plan on April 30, 2010.
(2) Represents an award of Restricted Stock Units that began vesting in 4 equal annual installments beginning on January 1, 2010.
(3) Represents an award of Restricted Stock Units that vest in 4 equal annual installments beginning on February 1, 2011.
(4) 25% of the total shares subject to the option vested on June 30, 2009, the first anniversary of the date of grant; the remaining shares continue to vest in 36 equal monthly installments thereafter.
(5) 25% of the total shares subject to the option vested on January 2, 2010, the first anniversary of the date of grant; the remaining shares continue to vest in 36 equal monthly installments thereafter.
(6) 25% of the total shares subject to the option vest on February 19, 2011, the first anniversary of the date of grant; the remaining shares will continue to vest in 36 equal monthly installments thereafter.

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