FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person * CRAWFORD SALLY   2. Issuer Name and Ticker or Trading Symbol HOLOGIC INC [HOLX] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director _____ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) 35 CROSBY DRIVE 3. Date of Earliest Transaction (Month/Day/Year) 10/22/2007 (Street) BEDFORD, MA 01730 4. If Amendment, Date Original Filed(Month/Day/Year) 10/24/2007 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock (1) (3) 10/22/2007   A   24,228 A (1) 24,228 D

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Nonqualified Stock Option

$ 65.63

10/22/2007

A

50,000

01/01/2008

10/22/2017

Common Stock

50,000

$ 0

50,000

D

Nonqualified Stock Option (2) (4)

$ 16.46

10/22/2007

A

12,302

10/22/2007

11/20/2009

Common Stock

12,302

(2)

12,302

D

Nonqualified Stock Option (2) (4)

$ 31.62

10/22/2007

A

12,302

10/22/2007

02/09/2011

Common Stock

12,302

(2)

12,302

D

Nonqualified Stock Option (2) (4)

$ 36.93

10/22/2007

A

12,302

10/22/2007

01/24/2012

Common Stock

12,302

(2)

12,302

D

Nonqualified Stock Option (2) (4)

$ 36.64

10/22/2007

A

12,302

10/22/2007

01/23/2013

Common Stock

12,302

(2)

12,302

D

Nonqualified Stock Option (2) (4)

$ 25.28

10/22/2007

A

43,058

10/22/2007

01/02/2011

Common Stock

43,058

(2)

43,058

D

Nonqualified Stock Option (2) (4)

$ 26.99

10/22/2007

A

34,600

10/22/2007

01/23/2011

Common Stock

34,600

(2)

34,600

D

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
CRAWFORD SALLY 35 CROSBY DRIVE BEDFORD, MA 01730	X

Signatures

/s/ Mark J. Casey, Atttorney-in-Fact For: Sally W. Crawford		01/18/2008
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	Received in exchange for shares of Cytyc Corporation common stock in connection with the merger of Cytyc Corporation with Nor'easter Corp., a wholly-owned subsidiary of Hologic, Inc. (the "Merger"). On the effective date of the Merger, the closing price of Hologic Inc.'s common stock was $65.63 per share.
(2)	Received in the Merger in exchange for an option to purchase shares of Cytyc Corporation common stock.
(3)	The amendment to the amount of securities beneficially owned following the reported transaction carries through to all forms November 7, 2007 through the Form 4 filed on January 8, 2008.
(4)	The amendments reported in this Form 4/A, including changes to the number of securities acquired, amount of securities underlying the derivative securities, number of derivative securities beneficially owned following reported transaction, exercise price and expiration date carry through the Form 4 filed on December 10, 2007. These items were correctly reported on the Form 4 filed on December 27, 2007 and the forms filed thereafter and no amendments are made to such filings by way of this amendment.

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