Washington, D.C. 20549


Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): April 20, 2004

BioMarin Pharmaceutical Inc.
(Exact name of registrant as specified in its charter)

Delaware 000-26727 68-0397820
(State or other jurisdiction of
 incorporation or organization)
File Number)
(IRS Employer
 Identification No.)

371 Bel Marin Keys Boulevard, Suite 210, Novato, California 94949
(Address of principal executive offices) (Zip Code)

Registrant's telephone number, including area code: (415) 506-6700

Not Applicable

(Former name or former address, if changed since last report)

Item 5. Other Events.

        On April 20, 2004, BioMarin Pharmaceutical Inc. (the “Registrant”), issued a press release regarding the Registrant’s entering into a definitive agreement with Medicis Pharmaceutical Corporation to obtain the Pediatrics Business of Medicis. The Registrant’s press release issued on April 20, 2004 is attached hereto as Exhibit 99.1.

Item 7. Financial Statements, Pro Forma Financial Statements and Exhibits.

    (a)        Financial Statements of Business Acquired.

                 Not Applicable.

    (b)        Pro Forma Financial Information.

                 Not Applicable.

    (c)        Exhibits.

                 Exhibit 99.1 Press Release of the Registrant dated April 20, 2004.


        Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

BioMarin Pharmaceutical Inc.,
a Delaware corporation

Date: April 21, 2004 By:  /s/Louis Drapeau  
      Louis Drapeau
      Chief Financial Officer


Exhibit No.          Description

Exhibit 99.1          Press Release of the Registrant dated April 20, 2004.