Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
SCHRODER VENTURE MANAGERS LTD
   2. Issuer Name and Ticker or Trading Symbol
Solexa, Inc. [SLXA] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
22 CHURCH STREET, 		 3. Date of Earliest Transaction (Month/Day/Year)
04/22/2005
(Street)

HAMILTON HM 11 BERMUDA, D0 0		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 04/22/2005 04/25/2005 P   330,730 A (15) 2,119,495 I See Footnote (1) (7)
Common Stock 04/22/2005 04/25/2005 P   140,857 A (15) 902,683 I See Footnote (2) (7)
Common Stock 04/22/2005 04/25/2005 P   37,538 A (15) 240,560 I See Footnote (3) (7)
Common Stock 04/22/2005 04/25/2005 P   9,511 A (15) 60,952 I See Footnote (4) (7)
Common Stock 04/22/2005 04/25/2005 P   40,736 A (15) 261,056 I See Footnote (5) (7)
Common Stock 04/22/2005 04/25/2005 P   5,102 A (15) 32,698 I See Footnote (6) (7)

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Warrant (right to buy) $ 5 04/22/2005 04/25/2005 P   165,365   10/25/2005 04/25/2010 Common Stock 165,365 (16) 165,365 I See Footnote (8) (14)
Warrant (right to buy) $ 5 04/22/2005 04/25/2005 P   70,428   10/25/2005 04/25/2010 Common Stock 70,428 (16) 70,428 I See Footnote (9) (14)
Warrant (right to buy) $ 5 04/22/2005 04/25/2005 P   18,769   10/25/2005 04/25/2010 Common Stock 18,769 (16) 18,769 I See Footnote (10) (14)
Warrant (right to buy) $ 5 04/22/2005 04/25/2005 P   4,756   10/25/2005 04/25/2010 Common Stock 4,756 (16) 4,756 I See Footnote (11) (14)
Warrant (right to buy) $ 5 04/22/2005 04/25/2005 P   20,368   10/25/2005 04/25/2010 Common Stock 20,368 (16) 20,368 I See Footnote (12) (14)
Warrant (right to buy) $ 5 04/22/2005 04/25/2005 P   2,551   10/25/2005 04/25/2010 Common Stock 2,551 (16) 2,551 I See Footnote (13) (14)

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
SCHRODER VENTURE MANAGERS LTD
22 CHURCH STREET
HAMILTON HM 11 BERMUDA, D0 0		     X    
SITCO Nominees Ltd. VC 01903 as Nominee of Schroder Ventures International Life Sciences Fund II Group Co-Investment Scheme
C/O GOODWIN PROCTER
53 STATE STREET
BOSTON, MA 02109		     X    
Schroder Ventures International Life Sciences Fund II Strategic Partners L.P.
C/O GOODWIN PROCTER
53 STATE STREET
BOSTON, MA 02109		     X    
Schroder Ventures International Life Sciences Fund II L.P.3
C/O GOODWIN PROCTER
53 STATE STREET
BOSTON, MA 02109		     X    
Schroder Ventures International Life Sciences Fund II L.P.2
C/O GOODWIN PROCTER
53 STATE STREET
BOSTON, MA 02109		     X    
SV (Nominees) LTD as Nominee of Schroder Ventures Investments LTD
C/O GOODWIN PROCTER
53 STATE STREET
BOSTON, MA 02109		     X    
SCHRODER VENTURES MANAGERS INC
787 SEVENTH AVENUE
29TH FLOOR
NEW YORK, NY 10019		     X    
SCHRODER VENTURES INTERNATIONAL LIFE SCIENCES FUND II LP1
787 SEVENTH AVENUE
34TH FLOOR
NEW YORK, NY 10019		     X    

Signatures

 /s/ Gary Carr   04/25/2005
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) These shares are owned directly by Schroder Ventures International Life Sciences Fund II L.P.1 ("ILSF LP1"). Schroder Venture Managers Inc. ("SVMI"), the general partner of ILSF LP1, and Schroder Venture Managers Limited ("SVML"), investment manager to SVMI, may be deemed to share voting and dispositive power over the shares held by ILSF LP1. SVMI and SVML disclaim beneficial ownership of shares held by ILSF LP1 except to the extent of any pecuniary interest therein.
(2) These shares are owned directly by Schroder Ventures International Life Sciences Fund II L.P.2 ("ILSF LP2"). SVMI, the general partner of ILSF LP2, and SVML, investment manager to SVMI, may be deemed to share voting and dispositive power over the shares held by ILSF LP1. SVMI and SVML disclaim beneficial ownership of shares held by ILSF LP2 except to the extent of any pecuniary interest therein.
(3) These shares are owned directly by Schroder Ventures International Life Sciences Fund II L.P.3 ("ILSF LP3"). SVMI, the general partner of ILSF LP3, and SVML, investment manager to SVMI, may be deemed to share voting and dispositive power over the shares held by ILSF LP3. SVMI and SVML disclaim beneficial ownership of shares held by ILSF LP3 except to the extent of any pecuniary interest therein.
(4) These shares are owned directly by SITCO Nominees Ltd. -- VC 01903 as Nominee for Schroder Ventures International Life Sciences Fund II Group Co-Investment Scheme ("Co-Invest"). SVMI and SVML, investment manager to SVMI, may be deemed to share voting and dispositive power over the shares held by Co-Invest because of a contractual relationship between Co-Invest and SVMI. SVMI and SVML disclaim beneficial ownership of shares held by Co-Invest except to the extent of any pecuniary interest therein.
(5) These shares are owned directly by SV (Nominees) Limited as Nominee for Schroder Ventures Investments Limited ("SVIL"). SVMI and SVML, investment manager to SVMI, may be deemed to share voting and dispositive power over the shares held by SVIL because of a contractual relationship between SVIL and SVMI. SVMI and SVML disclaim beneficial ownership of shares held by SVIL except to the extent of any pecuniary interest therein.
(6) These shares are owned directly by Schroder Ventures International Life Sciences Fund II Strategic Partners L.P. ("Strategic Partners"). SVMI, the general partner of Strategic Partners, and SVML, investment manager to SVMI, may be deemed to share voting and dispositive power over the shares held by Strategic Partners. SVMI and SVML disclaim beneficial ownership of shares held by Strategic Partners except to the extent of any pecuniary interest therein.
(7) ILSF LP1, ILSF LP2, ILSF LP3, Co-Invest, SVIL, and Strategic Partners (each a "Fund", or collectively the "Funds") may be deemed to beneficially own the shares held by each Fund because of certain contractual relationships among the Funds and their affiliates. The Funds disclaim beneficial ownership of shares held by any Fund except to the extent of any pecuniary interest therein.
(8) These warrants are owned directly by Schroder Ventures International Life Sciences Fund II L.P.1 ("ILSF LP1"). SVMI, the general partner of ILSF LP1, and SVML, investment manager to SVMI, may be deemed to share voting and dispositive power over the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by ILSF LP1. SVMI and SVML disclaim beneficial ownership of the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by ILSF LP1 except to the extent of any pecuniary interest therein.
(9) These warrants are owned directly by Schroder Ventures International Life Sciences Fund II L.P.2 ("ILSF LP2"). SVMI, the general partner of ILSF LP2, and SVML, investment manager to SVMI, may be deemed to share voting and dispositive power over the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by ILSF LP1. SVMI and SVML disclaim beneficial ownership of the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by ILSF LP2 except to the extent of any pecuniary interest therein.
(10) These warrants are owned directly by Schroder Ventures International Life Sciences Fund II L.P.3 ("ILSF LP3"). SVMI, the general partner of ILSF LP3, and SVML, investment manager to SVMI, may be deemed to share voting and dispositive power over the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by ILSF LP3. SVMI and SVML disclaim beneficial ownership of the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by ILSF LP3 except to the extent of any pecuniary interest therein.
(11) These warrants are owned directly by SITCO Nominees Ltd. -- VC 01903 as Nominee for Schroder Ventures International Life Sciences Fund II Group Co-Investment Scheme ("Co-Invest"). SVMI and SVML, investment manager to SVMI, may be deemed to share voting and dispositive power over the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by Co-Invest because of a contractual relationship between Co-Invest and SVMI. SVMI and SVML disclaim beneficial ownership of the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by Co-Invest except to the extent of any pecuniary interest therein.
(12) These warrants are owned directly by SV (Nominees) Limited as Nominee for Schroder Ventures Investments Limited ("SVIL"). SVMI and SVML, investment manager to SVMI, may be deemed to share voting and dispositive power over the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by SVIL because of a contractual relationship between SVIL and SVMI. SVMI and SVML disclaim beneficial ownership of the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by SVIL except to the extent of any pecuniary interest therein.
(13) These warrants are owned directly by Schroder Ventures International Life Sciences Fund II Strategic Partners L.P. ("Strategic Partners"). SVMI, the general partner of Strategic Partners, and SVML, investment manager to SVMI, may be deemed to share voting and dispositive power over the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by Strategic Partners. SVMI and SVML disclaim beneficial ownership of the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by Strategic Partners except to the extent of any pecuniary interest therein.
(14) ILSF LP1, ILSF LP2, ILSF LP3, Co-Invest, SVIL, and Strategic Partners (each a "Fund", or collectively the "Funds") may be deemed to beneficially own the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by each Fund because of certain contractual relationships among the Funds and their affiliates. The Funds disclaim beneficial ownership of the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by any Fund except to the extent of any pecuniary interest therein.
(15) These shares of Common Stock were acquired for approximately $4.00 per share.
(16) An unspecified percentage of the total consideration paid for the shares of Common Stock represents consideration for the Warrants.

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