COMMISSION FILE NUMBER
                                                                 1-11596

                                                              CUSIP NUMBER
                                                               714157-10-4

                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                   FORM 12b-25

                           NOTIFICATION OF LATE FILING

(Check One):   [X] Form 10-K    [ ] Form 20-F    [ ] Form 10-Q    [ ] Form N-SAR
               [ ] Form N-CSR

For Period Ended: December 31, 2005
[ ] Transition Report on Form 10-K
[ ] Transition Report on Form 20-F
[ ] Transition Report on Form 11-K
[ ] Transition Report on Form 10-Q
[ ] Transition Report on Form N-SAR
For the Transition Period Ended:

  Read Instruction (on back page) Before Preparing Form. Please Print or Type.
      Nothing in this form shall be construed to imply that the Commission
                 has verified any information contained herein.

If the notification relates to a portion of the filing checked above, identify
the Item(s) to which the notification relates:

--------------------------------------------------------------------------------

PART I -- REGISTRANT INFORMATION

PERMA-FIX ENVIRONMENTAL SERVICES, INC.

--------------------------------------------------------------------------------
Full Name of Registrant

--------------------------------------------------------------------------------
Former Name if Applicable

1940 NORTHWEST 67TH PLACE
--------------------------------------------------------------------------------
Address of Principal Executive Office (Street and Number)

GAINESVILLE, FLORIDA 32653
--------------------------------------------------------------------------------
City, State and Zip Code



--------------------------------------------------------------------------------

PART II -- RULES 12b-25(b) AND (c)

--------------------------------------------------------------------------------
If the subject report could not be filed without unreasonable effort or expense
and the registrant seeks relief pursuant to Rule 12b-25(b), the following should
be completed. (Check box if appropriate)

    (a) The reasons described in reasonable detail in Part III of this form
        could not be eliminated without unreasonable effort or expense;

[X] (b) The subject annual report, semi-annual report, transition report on Form
        10-K, Form 10KSB, 20-F, 11-K or Form N-SAR, or portion thereof, will be
        filed on or before the fifteenth calendar day following the prescribed
        due date; or the subject quarterly report or transition report on Form
        10-Q, 10QSB or portion thereof, will be filed on or before the fifth
        calendar day following the prescribed due date; and

    (c) The accountant's statement or other exhibit required by Rule 12b-25(c)
        has been attached if applicable.

--------------------------------------------------------------------------------
PART III -- NARRATIVE

State below in reasonable detail the reasons why Forms 10-K, 20-F, 11-K, 10-Q,
N-SAR, N-CSR, or the transition or portion thereof, could not be filed within
the prescribed time period.

    The registrant will not file its Form 10-K by March 16, 2006, because it
will be unable to complete the preparation of its consolidated financial
statements by the initial filing date without unreasonable effort or expense
due, in part, to the additional work that was required to complete management's
assessment of internal controls over financial reporting in accordance with
Section 404 of Sarbanes-Oxley. The registrant continues to dedicate significant
resources to the audit of the financial statements.

--------------------------------------------------------------------------------
PART IV -- OTHER INFORMATION

(1) Name and telephone number of person to contact in regard to this
    notification:

     RICHARD T. KELECY                 352                     395-1351
    ------------------         ------------------         ------------------
          (Name)                   (Area Code)            (Telephone Number)

(2) Have all other periodic reports under Section 13 or 15(d) of the Securities
    Exchange Act of 1934 or Section 30 of the Investment Company Act of 1940
    during the preceding twelve months or for such shorter period that the
    registrant was required to file such report(s) been filed? If the answer is
    no, identify report(s). [X] YES   [ ] NO

(3) Is it anticipated that any significant change in results of operations from
    the corresponding period for the last fiscal year will be reflected by the
    earnings statements to be included in the subject report, or portion
    thereof?                [X] YES   [ ] NO

    If so, attach an explanation of the anticipated change, both narratively and
    quantitatively, and, if appropriate, state the reasons why a reasonable
    estimate of the results cannot be made.

    The registrant estimates that it will have net income for fiscal year 2005
of approximately $3.7 million, as compared to a net loss of $19.4 million for
fiscal year 2004. The change is due in large part to a recovery from the losses
in 2004, from the discontinued operation, and write-downs as a result of
impairment of fixed and intangible assets, as more fully described in the
registrant's Form 10-K for the year ended December 31, 2004.

                                        2


--------------------------------------------------------------------------------

                     PERMA-FIX ENVIRONMENTAL SERVICES, INC.
                 -----------------------------------------------
                  (Name of Registrant as Specified in Charter)

has caused this notification to be signed on its behalf by the undersigned
thereunto duly authorized.

Date: March 15, 2006                              By: /s/ Richard T. Kelecy
                                                      --------------------------
                                                      Richard T. Kelecy
                                                      Chief Financial Officer

INSTRUCTION: The form may be signed by an executive officer of the registrant or
by any other duly authorized representative. The name and title of the person
signing the form shall be typed or printed beneath the signature. If the
statement is signed on behalf of the registrant by an authorized representative
(other than an executive officer), evidence of the representative's authority to
sign on behalf of the registrant shall be filed with the form.

                                    ATTENTION

            Intentional misstatements or omissions of fact constitute
               Federal Criminal Violations (See 18 U.S. C. 1001).

                              GENERAL INSTRUCTIONS

1.  This form is required by Rule 12b-25 (17 CFR 240, 12b-25) of the General
    Rules and Regulations under the Securities Exchange Act of 1934.

2.  One signed original and four conformed copies of this form and amendments
    thereto must be completed and filed with the Securities and Exchange
    Commission, Washington, D.C. 20549, in accordance with Rule 0-3 of the
    General Rules and Regulations under the Act. The information contained in or
    filed with the Form will be made a matter of public record in the Commission
    files.

3.  A manually signed copy of the form and amendments thereto shall be filed
    with each national securities exchange on which any class of securities of
    the registrant is registered.

4.  Amendments to the notifications must also be filed on Form 12b-25 but need
    not restate information that has been correctly furnished. The form shall be
    clearly identified as an amended notification.

5.  Electronic Filers: This form shall not be used by electronic filers unable
    to timely file a report solely due to electronic difficulties. Filers unable
    to submit a report within the time period prescribed due to difficulties in
    electronic filing should comply with either Rule 201 or 202 of Regulation
    S-T (Section 232.201 or Section 232.202 of this chapter) or apply for an
    adjustment in filing date pursuant to Rule 13(b) of Regulation S-T (Section
    232.13(b) of this chapter).

                                        3