FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person * Gupta Dinesh C.   2. Issuer Name and Ticker or Trading Symbol Semler Scientific, Inc. [SMLR] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director _____ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) 777 NORTH 1ST STREET, SUITE 720 3. Date of Earliest Transaction (Month/Day/Year) 02/26/2014 (Street) SAN JOSE, CA 95112 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 02/26/2014   C(1)   105,556 A (1) 105,556 I By Satwik Mezzanine Fund I, LLC (3) Common Stock 02/26/2014   C(1)   11,111 A (1) 11,111 I By Satwik Ventures I, LLC Defined Benefit Pension Plan (4) Common Stock 02/26/2014   M(2)   3,889 A $ 4.5 15,000 I By Satwik Ventures I, LLC Defined Benefit Pension Plan (4) Common Stock 02/26/2014   F(2)   2,501 D $ 7 12,499 I By Satwik Ventures I, LLC Defined Benefit Pension Plan (4) Common Stock 02/26/2014   M(2)   36,945 A $ 4.5 36,945 I By First Guardian Group I, LLC (5) Common Stock 02/26/2014   F(2)   23,751 D $ 7 13,194 I By First Guardian Group I, LLC (5)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Series A Convertible Preferred Stock

(1)

02/26/2014

C(1)

105,556

(1)

(1)

Common Stock

105,556

$ 0

0

I

By Satwik Mezzanine Fund I, LLC (3)

Series A Convertible Preferred Stock

(1)

02/26/2014

C(1)

11,111

(1)

(1)

Common Stock

11,111

$ 0

0

I

By Satwik Ventures I, LLC Defined Benefit Pension Plan (4)

Series A Preferred Stock Warrant (right to buy)

$ 4.5

02/26/2014

M(2)

36,945

07/01/2013

07/31/2016

Common Stock

36,945

$ 0

0

I

By First Guardian Group I, LLC (5)

Series A Preferred Stock Warrant (right to buy)

$ 4.5

02/26/2014

M(2)

3,889

07/01/2013

07/31/2016

Common Stock

3,889

$ 0

0

I

By Satwik Ventures I, LLC Defined Benefit Pension Plan (4)

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Gupta Dinesh C. 777 NORTH 1ST STREET SUITE 720 SAN JOSE, CA 95112	X

Signatures

/s/ Douglas Murphy-Chutorian, attorney-in-fact		02/27/2014
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	These securities automatically converted into Issuer's common stock on a one-for-one basis upon consummation of Issuer's initial public offering ("IPO") and had no expiration date.
(2)	These securities were cashlessly exercised immediately prior to Issuer's IPO and automatically converted into shares of Issuer's common stock on a one-for-one basis.
(3)	Mr. Gupta is a general partner and an investor in Satwik Mezzanine Fund I, LLC. Mr. Gupta disclaims beneficial ownership of the reported securities except to the extent of his pecuniary interest therein.
(4)	These securities are held for the benefit of Mr. Gupta.
(5)	Mr. Gupta is a general partner and an investor in First Guardian Group I, LLC. Mr. Gupta disclaims beneficial ownership of the reported securities except to the extent of his pecuniary interest therein.

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