The markets opened lower with the Dow losing 20 points to 21,591 on disappointing earnings. Nasdaq slipped 7 points to 6,383.

On the upside

Capital One Financial (NYSE: COF) reported higher second quarter earnings that beat expectations.

Encana (NYSE: ECA) reversed year ago losses to post a stronger than expected profit for the second quarter and lifted its core asset production growth forecast for the year.

Shares of Sarepta Therapeutics (Nasdaq: SRPT) extended its gains.

On the downside

Maxim Integrated Products (Nasdaq: MXIM) disappointed with fourth quarter earnings and revenue that fell short of expectations.

Second quarter earnings for Gentex (Nasdaq: GNTX) missed analyst estimates.

NCR (NYSE: NCR) reported lower second quarter revenue.

In the broad market, declining issues outpaced advancers by a margin of 3 to 2 on the NYSE and by more than 9 to 8 on Nasdaq. The broader S&P 500 fell 6 points to 2,467. Bitcoin gained $13 to $2687.